Tag: polio

  • Paul Richard Alexander: Living in an Iron Lung for 70 Years

    Paul Richard Alexander: Living in an Iron Lung for 70 Years

    Paul Richard Alexander was disabled at age 6 by a case of poliovirus. He was born on January 10, 1946, in Dallas, and he contracted the disease before the American form of the vaccine was developed. Paul was paralyzed almost entirely and placed in an “iron lung.” For 70 years, he has spent only a few moments of his daily life outside of his iron lung machine. Despite that, he became a lawyer and an author.

    Paul Richard Alexander is a role model for people with disabilities who want to succeed in life despite their difficulties because he completed high school, went to college, and became a practicing lawyer who has appeared in court hearings. He even published a book in 2020, typing on a keyboard with a stick he held in his mouth. Paul Alexander is 77 years old today.

    Paul Richard Alexander’s Disease and the Iron Lung

    Paul Richard Alexander (Paul Alexander) in the iron lung.
    At 74 years old, Paul Alexander began to stay in the iron lung for most of the time. He is 77 today. (Mitch Summers/YouTube)

    The highly contagious virus Paul Richard Alexander contracted is called poliomyelitis. Paul was six years old in 1952 when a polio epidemic swept through the Dallas neighborhood where he and his family lived.

    It was the biggest outbreak in the history of the United States, killing hundreds daily, mostly children.

    A week after his symptoms first appeared, they deteriorated dramatically. At this point, Paul was not able to talk. He was brought to Parkland Hospital, where he joined hundreds of other critically ill children.

    Paul Richard Alexander (Paul Alexander) as a kid
    Paul Richard Alexander as a kid (colored from the original).

    After some time, Paul Richard Alexander’s sickness rendered him unable to breathe on his own, so he was put in an iron lung, which is a negative-pressure mechanical respirator with a covered aperture for the patient’s neck.

    Paul was in the hospital for a total of 18 months, and he was in the iron lung the entire time. In the eyes of doctors, Paul initially had no chance of recovery. However, he had a strong will to live and was making miracle progress in his recovery.

    What is an iron lung?

    The first “iron lung” was developed in 1927, and subsequent refinements were made in the 1950s in response to widespread polio epidemics. The device is an enclosed pressure chamber large enough to fit a human, within which a pressure different from atmospheric pressure is created. The “iron lung” helps a person who cannot move his muscles to breathe by pumping air into and out of his lungs at varying pressures.

    Paul Richard Alexander (Paul Alexander) and his iron lung machine during one of the treatment sessions.
    Paul Richard Alexander and his iron lung machine during one of the treatment sessions.

    In 1954, his parents brought the machine and their son home, where they set him up with a physical trainer who specialized in helping those with paralysis of the breathing muscles learn to breathe through their mouths.

    Paul Richard Alexander was taught by the doctor to breathe like a free diver, using the glossopharyngeal method.

    The technique is based on drawing oxygen into the lips and using the motions of the tongue to force it into the trachea and lungs. After contracting polio, Paul was not able to breathe like other people since the diaphragm is also made of muscles.

    Paul Alexander is drawing with a brush he is holding in his mouth as a kid.
    Paul Alexander is drawing with a brush he is holding in his mouth.

    His parents rewarded him with a dog after he spent a year training to stay outside his iron cage for three whole minutes. After practicing glossopharyngeal breathing for three years, Paul Richard Alexander was able to go for several hours without his iron lung.

    In his younger years, Paul refused the practice of sitting at home and tried to attend parties and clubs, just like other people, and also prayed at church and traveled on planes and ocean liners.

    During his adulthood, he led and joined a sit-in protesting for the rights of people with impairments.

    Paul Richard Alexander’s Academic Life

    Paul Richard Alexander (Paul Alexander)

    After mastering the unusual breathing technique, Paul started school and learned quickly by memorization since he was not able to take notes. Just like Franklin Roosevelt, who contracted polio as a child and was paralyzed below the waist, Paul was an ambitious child who dreamed of becoming president.

    Paul Richard Alexander continued his education despite obstacles. He was one of the first students registered in the Dallas Independent School District’s distance education program in 1959 at the age of 13.

    He graduated from high school (W.W. Samuell High School) at the age of 21. He became the first high school student ever to graduate from high school through a distance education program.

    Simultaneously, Paul Richard Alexander had only “fives” and one “four” on his graduation certificate. He got a “4” in biology because he was paralyzed and therefore unable to dismember an animal.

    After completing high school, Paul took and passed the university entrance exams. But despite his good grades, the rector’s office still denied him admission based on his disability.

    Paul Richard Alexander Paul Alexander on his birthday
    Paul Richard Alexander on his birthday. (Mitch Summers/YouTube)

    Paul surmounted the rector’s opposition with the help of his instructors in high school. After two years of struggle, he registered at Southern Methodist University in Dallas, finished, and then attended the University of Texas School of Law in Austin.

    In Paul’s classroom, he was the only student with a disability.

    Paul used a wheelchair for transportation around the campus. However, he spent the vast majority of his time in the “iron lung,” where he also studied. This happened as a result of persistent feelings of embarrassment.

    Paul Richard Alexander’s presence at the university in a wheelchair garnered media attention because, in the 1960s, the United States had no federal disability inclusion initiatives and people with impairments were not prominent in society.

    Paul Richard Alexander graduated from college with a bachelor’s degree in 1978. He attended law school after finishing university, earned his Juris Doctor (J.D.) in 1984, and was admitted to private law practice in 1986 after passing the bar exam.

    A Career as a Lawyer and His Retirement

    With the help of his friends, Paul Alexander went to college, and became a practicing lawyer.
    With the help of his friends, Paul Richard Alexander went to college, and became a practicing lawyer. (Dream Big/YouTube)

    In order to help him out after he graduated from law school, Paul Richard Alexander employed Kathy Gaines. To this day, she has provided both work and care support to Paul from her home next door.

    Since he was already able to handle his own difficulties, many people believed that Paul would be able to handle judicial disputes with ease.

    In his time as a lawyer, Paul Alexander has dealt with wills, estates, social security conflicts, criminal trials, civil trials, cases involving minors, and business and governmental issues in court.

    As he got older, Paul’s stamina gradually declined. When he was over the age of 70, he could no longer muster the stamina to spend more than a few minutes outside of his iron lung. At 74 years old, he began to stay in the iron lung almost all the time because he needed the respirator to breathe. Today, Paul Richard Alexander is 77 years old.

    In 2020, Paul became the only living person using an iron lung. 2022 marked the year Paul Alexander used his iron lung for 70 years, which earned him a place in the Guinness Book of Records as the longest-living individual in an iron lung.

    Paul Alexander is still using his iron lung in the bedroom of his modest Dallas apartment.

    Paul Richard Alexander Published a Book

    Paul Richard Alexander's book: Three Minutes for a Dog: My Life in an Iron Lung

    Paul and his friend Norman D. Brown published an autobiography book in 2020 titled Three Minutes for a Dog: My Life in an Iron Lung. It was Kathy Gaines who came up with the name of the book.

    During the making of the book, Paul conveyed the words to his friend verbally, and he also wrote many of the pages himself, using a pencil he held in his mouth and typing on a keyboard using it.

    The first writing implement Paul could use was a flat stick with a fountain pen attached to the end, which his father fashioned for him. In time, his father crafted an assortment of sticks for various uses. Paul put them to use in his writing, drawing, and typing.

    The Discontinuation of Paul’s Iron Lung Machine

    In the late 1960s, iron lung machines stopped being produced. Paul’s machine sometimes broke, and he didn’t want to switch to a breathing tube, which would have required a tracheostomy (hole in the throat) and forced him to change his way of life completely. Due to the risks of having a tracheostomy, Paul did not want to have a hole in his neck.

    In 2018, the United States was home to all three of the world’s operational iron lung machines. After the air pressure in his iron lung failed in 2015, Paul’s friends helped him find an expert by posting a YouTube video, who was able to restore his respiratory equipment.

    Because no living technicians or engineers are left to maintain these devices. After the vaccine was developed, there was no longer a requirement to educate people on how to care for the iron lungs.

    Brady Richards was an expert mechanic and engineer who worked at the Environmental Testing Laboratory and whose hobby was fixing racing cars. He deduced the iron lung’s design, created replacement parts, and got Paul’s “lungs” back in working order.

    Paul Richard Alexander’s Private Life

    Paul Richard Alexander around his friends and family
    (Gizmodo/YouTube)

    During his college years, Paul was engaged to a fellow student named Claire, but the engagement was called off after Claire’s parents prohibited her from keeping in touch with Paul. So, Paul put off tying the knot forever.

    Paul developed an intimate, strictly professional connection with his caregiver and aide, Kathy Gaines.

    In 2018, Paul saw Sue Perry, who had been by his side in the polio unit 65 years ago for the same illness. She was 4 years old at the time, and she was not as severely affected by the poliovirus as Paul was, so she made a full recovery. When she learned that Paul Richard Alexander was alive, Sue immediately tracked him down.

    As of today, all of Paul Richard Alexander’s family members have predeceased him, including his elder brother Nick.

    Paul Richard Alexander with his family
    (Gizmodo/YouTube)

    History of Polio Disease

    During the epidemic that affected Paul Richard Alexander, there were a total of 58,000 cases of polio, over 21,000 cases of disability, and around 3,150 cases of death in the United States.

    There were global polio infections before the vaccine was developed in 1955. In the 1940s and 1950s, poliovirus was widespread, causing the deaths or paralysis of an estimated 600,000 individuals worldwide annually.

    The highly contagious viral illness Paul Richard Alexander contracted is called poliomyelitis. Children younger than 5 years old are particularly vulnerable to contracting poliomyelitis. The poliovirus can impair the nervous system and cause spinal cord damage, just like it happened with Paul Richard Alexander.

    Today, the World Health Organization estimates that polio causes general disability in 1 out of every 200 cases.

    Paul Richard Alexander at a Glance

    Who is Paul Richard Alexander?

    Paul Richard Alexander was born on January 10, 1946, in Dallas, and contracted poliomyelitis when he was 6 years old, before the American vaccine was developed. As a result, he became almost entirely paralyzed and was placed in an “iron lung” where he has spent almost every moment of his life for the last 70 years. Despite his disability, he became a lawyer and author and published a book in 2020 by typing on a keyboard with a stick he held in his mouth.

    How did Paul Richard Alexander become a lawyer?

    After completing high school through a distance education program, Paul Richard Alexander was denied admission to university because of his disability. With the help of his instructors in high school, he overcame this opposition and attended Southern Methodist University in Dallas, where he finished and then attended the University of Texas School of Law in Austin. He became a practicing lawyer who has appeared in court hearings and even published a book in 2020, typing on a keyboard with a stick he held in his mouth.

    What is an iron lung, and how does it work?

    An “iron lung” is a negative-pressure mechanical respirator with a covered aperture for the patient’s neck. The device is an enclosed pressure chamber that creates a pressure different from atmospheric pressure large enough to fit a human. The “iron lung” helps a person who cannot move his muscles to breathe by pumping air into and out of his lungs at varying pressures. The machine was first developed in 1927 and later improved in the 1950s in response to widespread polio epidemics.

    How did Paul Richard Alexander breathe without his iron lung machine?

    After contracting polio, Paul Richard Alexander was unable to breathe like other people, and his parents brought the iron lung machine home. They set him up with a physical trainer who specialized in helping those with paralysis of the breathing muscles learn to breathe through their mouths. He was taught by the doctor to breathe using the glossopharyngeal method. The technique is based on drawing oxygen into the lips and using the motions of the tongue to force it into the trachea and lungs. After practicing glossopharyngeal breathing for three years, Paul Richard Alexander was able to go for several hours without his iron lung.

  • History of Polio and the Invention of the Vaccine

    History of Polio and the Invention of the Vaccine

    It had been 60 years since the discovery of X-rays, which shook the world more than any medical development had. Then a development took place in 1955 that would have the same type of impact, and it was the vaccine for polio. The news on TV, scared parents who were worried about their kids, and the fact that a well-liked leader (Franklin Delano Roosevelt, the 32nd President of the United States) had the same disease all made everyday life worse.

    Polio disease spreads

    This development brought the most precious gift to humanity by taking it away from its fears: the fear of catching paralytic poliomyelitis (which is more commonly known as polio) that arises every summer. In the United States, there were 25,000 cases of poliomyelitis per year, and the disease had a deep-rooted history that dates back to the Ancient Egyptians.

    However, the outbreaks in the 1920s, 30s, and 40s were gradually causing more and more deaths. Many children and young people died due to illness, and those who remained crippled or paralyzed lived the rest of their lives connected to a mechanical respirator called “Iron Lung,” which looked like a gigantic tank. Experts predicted that outbreaks would worsen in the 1950s.

    The 1952 epidemic was the most terrifying epidemic recorded. Approximately 58,000 people were infected, and 3,000 were dead. In addition to this tragedy, expressed in thousands, the anxiety and fear felt in the summer were very wearying. Every person who had witnessed that period could not forget the happenings.

    The invention of the polio vaccine

    Dr. Jonas Salk invented the first solution to the polio vaccine.
    Dr. Jonas Salk invented the first solution to the polio vaccine.

    In early 1955, the public’s primary concern was the minor successes achieved with the vaccine being developed against the poliovirus. Later, Dr. Thomas Francis of the University of Michigan (who bears his father’s name) said in a press conference on April 12 that approximately one million people, 440,000 of whom are children, were vaccinated with Dr. Jonas Salk’s vaccine, which “kills the poliovirus.”

    This news echoed all over the world, showing the joy and relaxation seen in people’s faces. President Dwight Eisenhower praised Dr. Salk as a “benefactor of mankind”. American Medical Association President Dwight H.

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    Murray heralded this development as “one of the greatest events in the history of medicine.”

    The development of the virus preparation methods in laboratories with animal tissue culture techniques and the use of all three types of poliovirus to make an effective vaccine are the two most important factors behind the invention of the polio vaccine. Dr. John Enders of Harvard University was awarded the Nobel Prize in Medicine for the tissue culture method.

    Viruses in the Salk vaccine were first replicated in monkey kidney cells and then inactivated with formaldehyde solution.

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    Salk became a national hero after his vaccine was declared safe, potent, and effective. In public opinion polls, he became one of the people who went down in history and got votes close to Churchill and Gandhi.

    Colleagues ignore Salk

    salk2

    Salk was engaged with philosophy in the following years, and he believed that it is the power of development that directs his work, “Development is not only an effective process that I live in any moment but also a phenomenon that I can direct and shape with the choices I make. I always feel the next developmental stage in myself. This is not something everyone can do, only some of us can do that.” But unlike the public, who embraced him, he was deeply hurt by his colleagues’ ignoring his work and not showing the necessary respect.

    Al Rosenfeld, senior editor of Life magazine and also a close friend of Salk, stated that “it is very tragicomic for a man who is so exalted in the eyes of the public to win the praise of only a few colleagues for his work.” Despite his achievements, he was not deemed worthy of the Nobel Prize or accepted as a member of the American Academy of Sciences.

    The disappointment of his assistant

    Dr. Julius Youngner
    Dr. Julius Youngner

    Dr. Julius S. Youngner’s thoughts on Salk, who was Salk’s number one assistant in the team working on the polio vaccine:

    “At first, I saw Salk as a father, but as time went on, this idea changed; he turned into a horrible man in my eyes. (…) He took all the money paid for the vaccine we developed, and he was responsible for all administrative affairs. He was doing everything. There were too many politicians involved in our business. One day I saw him answering press members’ questions. He sounded as if he had done everything alone. Everyone wants to be praised for what they do.

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    Unfortunately, he escaped from us and deprived us of these compliments. It took me a long time to understand this. I do not think that someone I admire and trust so much has done such a thing to me and my colleagues.”

    Salk responded to such criticism about putting himself forward and said:

    “Perhaps a more conscious attempt might have been made and perhaps should have been made to list the names of each individual more prominently rather than, as was implied, that the satisfaction came from the work itself.”

    Although some of his teammates criticized him for collecting all the applause, he was also subjected to tougher and more serious criticism because of his behavior and work. Many of these criticisms were made by Dr. Salk’s competitor, Albert Sabin, about his (weakened) polio vaccine.

    The perfect vaccine for polio

    The iron lung or tank ventilators were the only way to keep polio patients alive in the 1940s and 50s.
    The iron lung or tank ventilators were the only way to keep polio patients alive in the 1940s and 50s.

    Albert Sabin (1907-1993) was a genius virologist who made important contributions to the scientific world about how the poliovirus was transmitted to humans before World War II. It was he who found that the poliovirus enters the body through the mouth, passes through the digestive system, then settles in the nerves and devastates them.

    During the war, he developed effective methods for combating viral diseases that weakened army troops. Because of these things, in 1951 he was invited to join the American Academy of Sciences.

    After the war, he returned to his poliovirus studies and began working on live vaccines (live polio vaccine), which included three pathogenic, highly weakened, harmless polioviruses. According to Sabin, this vaccine that uses the weakened form of the live virus has many advantages over the vaccines with dead viruses.

    Firstly, it could be given orally in a sugar cube without any injections; unlike repeated injections of other vaccines, a single oral dose of live vaccine would provide lifelong immunity; and like the real poliovirus, the virus that entered the body from a live vaccine could be excreted through feces.

    The vaccine is distributed around the world

    Salk had launched a campaign against Sabin’s vaccine. However, Sabin was right in all respects in presenting this vaccine to the public. Still, in 1958-59, he was sent to the Soviet Union to test his vaccine. The Salk vaccine significantly reduced polio cases between 1955 and 1962.

    But when the Sabin vaccine was tested on 180,000 children in Cincinnati in 1960, it yielded spectacular results and was later licensed by the American Public Health Association in 1962. Since then, the vaccine has been used to protect against polio in the United States and many other countries.